Is it possible to replace the radiator support bushings in a '69 with it still in the car. Before I attempt it just want to make sure they will come out without having to remove the fender, etc. I'm guessing I should be able to slightly pry up on the support just enough to get the bottom bushing out of the hole in the subframe.

I would think one could lift the front sheet metal up high enough to remove the top half of the bushing. Check for clearance at the bumper brackets and maybe disconnect the bumper end supports.

The bumpers are attached to the frame and the corners are attached to a corner bracket at the junction of the fender and fender extension.

Yes you can replace the bushings without taking apart the whole car.

Check out the URL I provided you below. It is a web page from a camaros.net member. He provides good instructions for removing and replacing all of your sub frame bushings without taking apart the car. I followed them and was able to swap out all 6 bushings so you should have no problem replacing just the front ones.
Replacing Sub Frame Bushings web page (http://www.geocities.com/boodlefoof/bushings.html)

You may have to loosen all three sub frame bolts on one side just to get out the front bushing your after.

Thanks jrager, good link. Sounds easier than I thought. I'm just going to do all six of mine since all are deteriorated.

Larry I did this swap over the winter. Wasn't to bad, call if need any help. John