Brian, why are we getting these? Is this site now a medium for advertisers? If that's the case, then I won't be visiting any longer. I don't go to any sites that allow pop-ups.
Okay a few things to know. All load balanced websites are moving rapidly to so called cloud based hosting service platforms. Load balanced means that the actual website - greenwidget.com lives on hundreds of servers, and if you are Amazon.com maybe tens or hundreds of thousands of servers worldwide and as requests from your browser hit the named https://greenwidget.com
the load of all the current requests are spread across the entire number of servers up. So while you are in California your request could hit a server in Germany because its 2 am in Berlin and that side of the world has little traffic. This allows for almost 24/365 up time as taking one server down to run patches or load content has zero effect on the websites ability to serve content or sell widgets worldwide. Almost all of these cloud services offer high speed servers that actually are virtual, meaning hundreds of "servers" are running off one actual hardware server, as opposed to the old model of a server farm with thousands of servers in racks in a warehouse sucking up electricity and producing heat.
The top cloud platforms right now in the world are of course the largest Microsoft, followed closely by Amazon Cloud Services, and Google Cloud Services. Oracle, SAS, offer business based database platform as does Microsoft to name just a few. They all are designed to reduce the high costs of hosting websites, and for retail/goods and services customers the goal is to 100% monetize the visitors with either salable marketable data extraction, or through ad servicing on proven user trends. This is where the COOKIES cook you. So if you use Chrome your goose is double cooked, especially on a Google cloud based server. They know more about you than you now know. You are a commodity to be sold, and to be served other commodities and services.
So on to your question about the Amazon Prime Ads today...As I said it's not a pop-up ad it a special class of advertising called a hover ad because it does not have a window associated with it, which is why pop-up blockers fail to recognize it, and unless it has a close object you can't get rid of it. Hover ads stay on the center focus of your monitor even when you scroll.
Google has been rolling them out for months now to all clients who use their premier ad delivery system. Amazon is a major player, so is eBay. As we are hosted now in the center of the Google cloud, we are ground zero of the Google data spider web. All Google cloud sites get them part and parcel of the data stream. I suspect even if you are not a premier subscriber your feed will get them eventually as more sites incorporate code and services delivered from Google.
Only way to block them is to destroy the code that creates them. AdBlockPlus and NoScript do it very well. Painless actually.