You don't know 'the rest of the combination' but you're giving header advice? When it comes to advice, I'd take the advice of a professional header builder, like Jack Burns of Burns Stainless, Mark Lelchook of Performance Welding Racing Headers, or Ed Henniman of Headers by Ed. On the advice of Ed Henniman, I used 1-5/8" primaries with 2-1/2" collectors on my 406" daily driver Nova. In addition to towing trailers and getting 18 mpg on the open road, it ran 11.75 @ 117 in the quarter. I'll stick by Jack Burns statement about the primary and collector size, and Mark Lelchook offers the following advice:
So being very general, a low horsepower 350 CID V8 engine making only 1.5 horsepower per CID ( that's 525 hp ) may only require a primary tube size of 1 5/8" stepped to 1 Âľ". This particular engine would only require a merged collector throat size of approximately 2 ÂĽ" with a 3" outlet. The primary tube length is dictated by what RPM the engine is run at to obtain these power levels, with the vehicle weight, transmission, torque converter, and type of racing playing a dominating role.