Before you responded, I was going to say, it probably won't make a significant difference going from 4.10s to 3.73s in 1/4 mile, but it also won't do much to improve highway. If you're going to bother do anything, you'd want the 3.55s.
So the Autogearset is: 2.98-1st, 2.04-2nd,1.46-3rd, 1:1-4th correct? That'll drop your 1st gear multiplier from 12.2:1 to 10.6:1. That's still a great takeoff gear.
One thing you mentioned is the lack of difference shifting 5700 vs. 6200rpm. This may change with the slightly milder 3.55s. I think if you do the swap, maybe experiment different launch rpms and shift (even try varying it 2-3 vs. 3-4) and you'll probably get most of it back. At least it's not requiring you to use another gear you previously weren't, as that would be more time lost due to the gear-shift time. Plus the 3.55s will probably work better later on with the extra torque of the 383 if you go down that route later.